Ozone Therapy

Boost your maximum health potential with ozone therapy.

Watch the video : What is ozone therapy?

Just as we watch technology evolve at a rapid pace year after year, so too does the discovery of ways you can treat and nourish your body to boost your maximum health potential.  In addition to our High Potency IV Vitamin Therapy, Ozone Therapy offers a multitude of benefits to your body and in return your quality of life.

What is Ozone Therapy?

Ozone therapy involves introducing the Ozone molecules in specific ways to our body. The most common method is mixing it with our blood in an IV and reintroducing our ozonized blood back into our body. 

What is Ozone?

What is ozone therapy - Ozone (O3) is a highly reactive gas composed of three oxygen atoms.

Ozone (O3) is composed of three oxygen atoms

Ozone is a naturally occurring element found in our atmosphere. The ozone molecule (O3) contains three oxygen atoms whereas the oxygen molecule (O2) contains only two. Therefore, Ozone is a form of oxygen and can be produced by special technology in a doctor’s office.

History of Medical Ozone

Despite its dubious status in the USA as an “alternative” treatment, for the past 150 years Ozone Therapy has been thoroughly studied and widely utilized throughout Europe and Asia. For US patients who encounter it for the first time it’s an interesting and curious treatment, because it seems so simple, natural and effective, that one wonders why so few US doctors use it.

As a matter of fact, even though it is statistically one of the safest medical treatments known, until relatively recently, Ozone Therapy was illegal in many states, and patients had to travel to Mexico to find American doctors who practiced “Integrative Medicine” and whose specialization included Ozone Therapy.

The reasons for this negativity and resistance to ozone in the US are entirely political and commercial, (as many disruptive innovations encounter), and have nothing to do with what is good for patient care…. But this is a subject for another article.

Our Introduction to Ozone Therapy

At AMA Regenerative Medicine, we were introduced to Ozone Therapy by some of our patients who had been healed from various devastating cancers and microbial infections by American Integrative MD’s who had moved their offices to Mexico. Their stories were so compelling that we traveled with them to these clinics to learn firsthand about the mysterious ozone treatments. Thereafter, having validated their amazing recoveries with our own eyes, we traveled to Italy, the world’s center for ozone studies, to study Ozone Therapy with renowned global experts.

It was there in Italy that we learned about Ozone Therapy and how it is extremely effective in patients who are suffering from a wide variety of chronic microbial infections, fungal (yeast) such as Candida, Bacterial infections such as Spirochetes and Lyme Disease, MRSA infections and viruses such as Epstein Barr, Herpes (Simplex & Shingles), HIV and even Ebola, as well as a whole host of inflammatory diseases.

The Benefits of Ozone Therapy

Just a few of the many established beneficial effects of Ozone Therapy include: Dental caries (cavities), decreased blood cholesterol, increases red blood cell metabolism, increases oxygenation of tissues, increases mitochondrial production of ATP, preserves tissues suffering from hypoxic and ischemic conditions, and accelerates wound healing. Ozone Therapy comes with a long list of benefits as a complimentary medical approach in the treatment of various diseases:   

A patient receiving High Dose Ozone Therapy (aka The 10-Pass device)

A patient receiving High Dose Ozone Therapy (aka The 10-Pass device)

Additional Health Benefits Include

How Ozone Therapy Works

Ozone has different actions depending on its concentration and how it’s administered.  While ozone does have a direct killing effect on bacteria, funguses, protozoa and viruses, its main mechanisms of action are by stimulating (modulating) our natural physiological immune and regenerative systems.  Thus, ozone easily fits into the category of “biological therapy”, or “physiological therapy”.

Ozone has six primary modes of therapeutic significance:

1. Regenerative

Ozone injection into the shoulder

Ozone injection into the shoulder

By stimulating mitochondria, ozone supports and accelerates the body’s natural ability to heal damaged tissue and regenerate healthy tissue. Examples include ozone injections to heal damaged joints. It accomplishes this by stimulating the mitochondria of cells that are actively involved in regeneration, such as Stem Cells or the cells that generate new collagen in a damaged joint, or those that form new bones in the case of bone damage.

Note: Every cell in your body is dependent on ATP from which it derives the energy it needs to perform its functions. ATP is generated in mitochondria. Therefore, if your cells have more ATP, they function better. From cells that make collagen, to cells that make your hormones, or make natural antioxidants, or detox your blood… everything is dependent on the health of your mitochondria. Ozone is better at supporting the health of your mitochondria than any other known substance.

Interestingly, prokaryote cells which include all bacteria do NOT have mitochondria, so they are not helped by ozone.

2. Infectious Disease

Wherein ozone attacks pathogenic infections by bacteria, fungi, protozoa and viruses, and stimulates the body’s natural immune defenses. This form of physiological therapy is called Oxidative Therapy.

Note: Ozone attacks the cellular membranes (walls) of microbes, so all bacteria fungi, yeast and viruses are susceptible.

Note: Ozone is also a powerful stimulator of immune functions by increasing your generation of interferon, tumor necrosis factor and Interleuken-2. All of these are essential in a healthy immune response to microbial infection attacks.

Note: Bacteria can not develop resistance to ozone.

3. Cancer

Wherein ozone attacks malignant cells, and protects healthy cells. It can also be a powerful adjunctive therapy to chemotherapy. As in #2 above, this form of physiological therapy is Oxidative.

4. As a detox agent

DSAP (disseminated superficial actinic porokeratosis) before and after treatment with with high dose ozone therapy

DSAP (disseminated superficial actinic porokeratosis) before and after treatment with high dose ozone therapy

Ozone stimulates the body’s natural ability to generate its own anti-oxidants. This is particularly important for the health of the two organs that generate more oxidative activity than all other organs, namely, your liver and brain.

5. Anti-Oxidative Response

Ozone stimulates a powerful anti-oxidative response by our bodies and has proven effective in subduing the overproduction of inflammatory cells such as those associated with Asthma, Diabetes, as well as other painful inflammatory diseases like arthritis, Fibromyalgia and others.

6. Oxygenation

Ozone stimulates oxygen metabolism by empowering your red blood cells with greater cellular energy derived from glycolysis. This also increases the ability of your red blood cells to deliver greater quantity of oxygen to your tissues. This not only increases your body’s ability to regenerate new tissues, it directly attacks bacteria, who are anaerobic and are negatively affected in an oxygen rich environment.

For more information see: Ozone therapy: A clinical review from The National Center for Biotechnology Information

How Ozone is Administered

As the clinical evidence for the effectiveness of Ozone therapy is gaining recognition, there are now several clinics throughout the country that are having remarkable results treating chronic complex infections, like Lyme and various viral infections with ozone. 

Intravenous (IV)

The preferred method of administering ozone therapy is intensive intravenous (IV) ozone protocols.  The most effective of these therapies is Hyperbaric ozone therapy with the Hermann device, also known as “Ten Pass” therapy.   

Watch the video : Hyperbaric ozone therapy – The “ten pass” device

Most clinics combine ozone IV therapy with high potency vitamin IV therapy, for a synergistically fabulous impact on your overall health and wellbeing.


Ozone can be injected directly into joints and soft tissues.


Though Ozone is powerfully effective when administered as an IV, It has a similar effect when applied internally or topically in the form of ozonated oils such as olive oil.  (Nikola Tesla was the first to develop these medicinal oils for physicians).  Water can also be ozonated for drinking and bathing in.

Limb Bagging

Nasal insufflation of ozone for sinus problems

Nasal insufflation of ozone for sinus problems

Ozone gas, at precise concentrations, can be infused into a bag that is encapsulating a limb, (“limb bagging”), or used in ozone saunas.


Ozone can be infused directly into body cavities, called “insufflation”. (Rectal/colon, vaginal, ears, sinuses, bladder.) 

The Results

In each of these cases, the ozone treats localized infections, and supports an accelerated healing of the inflamed tissue. Bottom line, ozone therapy is safe, natural and works physiologically to eradicate all sorts of infections and boost your overall health and wellbeing.

Patient Stories – Their Experience with Ozone Therapy

Scott – My Experience with Ozone Injections for Joint Pain

“My name is Scott and I’m a contractor and body builder. Over the years of training I’ve destroyed my joints. As I got older I started having joint problems. My knees, shoulders, elbows, ankles, etc…

… I recommend anyone to try the ozone injections before they go and have surgery. I’ve been coming to AMA for my ozone injections and the people and the staff are wonderful.”

Allen – My Sinus Infection Treatment with Ozone Insufflation

“Hi my name is Allen and I came to AMA Regenerative Medicine for treatment of my chronic sinus infection. Over the last 8 to 10 years I’ve been suffering from chronic sinus infections…

… After just a couple of weeks the ozone injection and insufflation treatments have made a tremendous difference. The ozone treatments have been a miracle for me.”

Scot – My DSAP Healed & My Seizures Stopped with HDOT

“My name is Scot. I came here because of DSAP (disseminated superficial actinic porokeratosis) I had a subdural hematoma where there was a liter of blood on my brain. So I had brain surgery…

… I started the high dose ozone therapy in fall of 2018 and much to my amazement my arms and legs, which were just awful, began to heal. Much more than that I had these terrible, terrible seizures that were a result of the brain injury and they stopped. ”

Gavin – How I Quickly Recovered from Open Heart Surgery

“My name is Gavin. I had a quadruple bypass. I’m a glass artist and surfer. Pretty active person. I’ve been a vegetarian my whole life. ..

… I just feel every day that I’m getting stronger and healing faster and faster. I think just overall everything is getting better. I’m very grateful for being able to get the ozone and stem cells to help me recover fast from my quadruple bypass because I got work to do and a new higher purpose in life.”

Ron – My Stem Cell & Ozone Treatments for Longevity

“My name is Ron and I’m in my eighth decade of life. I’m here at AMA because they offer a number of longevity services, including stem cell therapy and ozone therapy, that I believe are very important to my long term health…

… After the ozone therapy treatment I notice I higher level of energy. I feel good all the time. When I tell people I am in my eighth decade of life there is a large amount of disbelief when I say that.”

Randy – Ozone Therapy Relieved Me of My Lyme Disease Symptoms

“My name is Randy and this the story of my Lyme disease and the treatment with ozone I received to relieve me from the symptoms of Lyme…

… I’ve tried probably every imaginable healing modality, I mean, every treatment for Lyme disease there is. I believe in ozone because at the end of the day it reduces my symptoms. I’m doing things that I wasn’t able to do prior to getting the treatments with the ozone.”

Former N.Y. Yankee Jim Leyritz – My Experience with Ozone and Stem Cell Injections

“I’m Jim Leyritz, former 2 time World Series Champion with the Yankees. I was a catcher in the major leagues for almost 20 years. I have been receiving Ozone and Stem Cell injections to help with my injuries and pain…

… I’m able to run again but more importantly I don’t have to take 6 to 10 Advil every day for the pain, for the swelling and things like that. My body is just naturally doing it because of the ozone injections and because of the treatments I am receiving with the ozone therapy.”

Ozone Therapy FAQs

A. A combination of Hyperbaric Ozone Therapy and Hyperbaric Oxygen Therapy has an excellent chance of stimulating significant healing of your AVN. The regeneration of damaged tissue is stimulated and by both therapies. Also, your native stem cells, which are at the heart of your situation, are known to be stimulated by Hyperbaric Ozone Therapy.

Another therapy that may be very beneficial to you is Stem Cell Therapy. Stem Cell Therapy is the single most effective regenerative therapy ever known. When combined with Hyperbaric Ozone Therapy the two produce maximal results.

A. Yes, Ozone Therapy is fantastic for arthritis. Ozone causes the reduction of pain and inflammation, and stimulates regeneration, when injected directly into an arthritic joint.

When ozone is infused into the blood, for those with rheumatoid arthritis, it reduces the systemic inflammation throughout the body that is caused by the autoimmune disease.

A. Ozone Therapy is very beneficial especially when combined with stem cell infusions. Multiple treatments will be needed. Ongoing maintenance treatments might be needed indefinitely depending on how severe your condition is.

A. Yes, ozone injections can be very healing for a herniated disk injury. Ozone stimulates the bodies natural regenerative processes and also reduces inflammation.

To encourage regeneration of the damaged tissue, most doctors with experience in ozone medicine will include specific vitamins and cellular nutrients along with the ozone. The injections themselves are typically painless. The most uncomfortable part of the procedure is the prick of the needle.

In the case of ozone injections into a joint, the pain disappears almost immediately. This is because an anesthetic is included in the formulation. Once the anesthetic has worn off, the pain is typically greatly diminished due to the effects of the ozone.

Following the injection, it is important not to over exert yourself for a few days. Be patient as the healing response of your physiology takes hold of healing the herniated disc. Natural healing is not a “transaction”, it is a process that needs to take its natural course. To maximize the healing, your herniated disk may require 3 to 5 strategically timed injections.

A. Yes, the ozone will help quite a bit but you will also need to detox from the effects of the Cipro.

There are Naturopathic doctors and Integrative doctors who are experts in this type of detox work. I am sure you can find one in your area.

 Quicksilver Scientific has the best detox protocols I have ever encountered.

A. Yes, it is a bad idea to have bubbles in the blood stream. This is something that never happens when Ozone Therapy is administered in the standard way.

A precise amount of blood is drained from the patient similar to giving blood. That blood is then infused with ozone and every drop of the patients blood is then dripped back into their body.

Statistically, Ozone Therapies are the safest medical treatment in history. Millions of these treatments are performed every year all over the world without any negative occurrences or serious incidents.

A. Yes, in our experience Ozone Therapy can help fibromyalgia.

A. Yes, Ozone Therapy is a powerful stimulant of your immune system,  As such it can help very much against all sorts of viruses. We have many patients with hepatitis and herpes who are having excellent results. 

The protocol needed is different for each patient depending on the severity of their symptoms.  Generally, patients start with 2-3 treatments per week for 4-6 weeks, and then, as they get better, we slowly reduce the treatments to once per week, then every other week, down to once per month.

A. To encourage the healing of a damaged joint we use 4 modalities together:

  1. Ozone gas, which reduces inflammation and stimulates collagen regeneration
  2. Clot Matrix, which is a fibrin clot derived from a small amount of the patient’s blood, which is especially rich in platelets.  These platelets are cells that store all sorts of biochemical mediators that stimulate healing and regeneration.
  3. A special mix of vitamins that are required for the generation of new healthy tissue
  4. Procaine, which anesthetizes the joint, making the procedure comfortable.  It also breaks the pain cycle.

Lastly, if warranted, we can add a fifth and most potent element of all, placental mesenchymal stem cells. Using these stem cells causes such powerful regeneration, that many people who are scheduled for total joint replacement surgery can often avoid the need for the surgery all together.

A. Ozone Therapy is very much dose dependent and the blood can only handle a specific concentration of ozone at one time. The goal is to get the optimum quantity of ozone into the patient’s blood.

However, the ozone can not be administered directly into the patient’s vein. Also, you can’t use too much ozone to over saturate a specific quantity of blood all at one time.

Therefore, administering ozone of the correct concentration into a measured quantity of blood and re-infusing the blood back into the patient is the only other option. This is repeated until the overall volume of the patient’s blood has been infused with the optimal quantity of ozone.

This is know as High Dose Ozone Therapy or HDOT. When done correctly, the therapeutic value of High Dose Ozone Therapy is stunning!

A. Yes. High Dose Ozone Therapy (HDOT) is known to be an effective treatment to increase mitochondrial function, reduce systemic inflammation and to stimulate the activity of native stem cells. All three of these are important for treating and healing multiple sclerosis.

The most promising treatment for MS utilizes a combination of High Dose Ozone Therapy with the use of mesenchymal stem cells. This mode of therapy has been documented to not only stop the progression of the MS, but even reverse it. Please watch the video… Stem Cell Treatments for Multiple Sclerosis – Sam Harrell 10-10-2015

A. If the ACL is NOT torn all they way through then ozone injections can help. Ozone injections are a very effective regenerative treatment that can definitely help a knee with a compromised ACL.

It is doubtful if ozone can help and ACL to reattach that is torn all the way through. In such cases, Stem Cell Therapy along with ozone has proven to be far more effective. This combination treatment often heals the joint completely without surgery.

There are now numerous clinical studies showing how Stem Cell Therapy has stimulated the regeneration of articular cartilage of bone-on-bone joints.

Authored by Dr. Asher Milgrom | Reviewed by Dr. Alice Pien | Last updated:  

Learn More About the Science of Ozone Therapy

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